Article
Associations of the estrogen receptors 1 and 2 gene polymorphisms with the metabolic syndrome in women.
Metabolic syndrome and related disorders - 1 Apr 2009
Goulart Alessandra C, Zee Robert Y L, Pradhan Aruna, Rexrode Kathryn M
Abstract excerpt
BACKGROUND: Genetic variation of the estrogen receptor alpha (ESR1) and beta (ESR2) has been associated with components of the metabolic syndrome. METHODS: The relationships of two ESR1 (rs2234693 and rs9340799) and three ESR2 (rs1271572, rs1256049, and rs4986938) polymorphisms with the metabolic syndrome were examined in 532 Caucasian female participants (median age 63.1 years) in the Women's Health Study. Most...
