Article
Severe obesity is associated with novel single nucleotide polymorphisms of the ESR1 and PPARgamma locus in Han Chinese.
The American journal of clinical nutrition - 1 Aug 2009
Chen Hsin-Hung, Lee Wei-Jei, Fann Cathy S J, Bouchard Claude, Pan Wen-Harn
Abstract excerpt
BACKGROUND: A large number of potential obesity loci have been reported. At least 18 genes have been replicated in a minimum of 5 studies on obesity-related phenotypes. Fourteen additional genes have been associated with obesity in Asians. OBJECTIVES: Our objectives were to examine how many common variants of these candidate genes are associated with severe obesity in Han Chinese and how they are combined to...
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