Article
Estrogen receptor 1 gene rs2295193 polymorphism and anorexia nervosa: new data and meta-analysis.
Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists - 1 Dec 2013
Zhang Chen, Chen Jue, Jia Xiuzhen, Yu Shunying, Jiang Wenhui, Zhang Ran, Yuan Aihua, Qian Yiping, Fan Juan, Zhang Mingdao, Fang Yiru, Xiao Zeping
Abstract excerpt
INTRODUCTION: Estrogen plays essential roles in the regulation of food intake, adiposity, and body weight control. The estrogen alpha receptor, encoded by estrogen receptor 1 gene (ESR1), has been implicated with anorexia nervosa (AN). A previous study indicated that the rs2295193 polymorphism in ESR1 may confer a genetic susceptibility to AN. METHODS: In a case-control study, we assessed 195 AN probands and 93...
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