Article
The 2.3 genotype of ESRRA23 of the ERR alpha gene is associated with a higher BMI than the 2.2 genotype.
Obesity research - 1 Oct 2005
Kamei Yasutomi, Lwin Htay, Saito Kyoko, Yokoyama Tetsuji, Yoshiike Nobuo, Ezaki Osamu, Tanaka Heizo
Abstract excerpt
ERR alpha (NR3B1) is an orphan nuclear receptor believed to be involved in energy metabolism and obesity. A 23-base pair sequence in the 5'-flanking region of the ERR alpha gene, referred to as ESRRA23, is polymorphic in human chromosomes. Here, we investigated the influence of the ESRRA23 polymorphism on obesity in 703 Japanese individuals by analyzing indices of obesity and related lifestyle factors. The...
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