Article
Studies on the role of NonA in mRNA biogenesis.
Experimental cell research - 1 Aug 2006
Kozlova Natalia, Braga José, Lundgren Josefin, Rino José, Young Patrick, Carmo-Fonseca Maria, Visa Neus
Abstract excerpt
The NonA protein of Drosophila melanogaster is an abundant nuclear protein that belongs to the DBHS (Drosophila behavior, human splicing) protein family. The DBHS proteins bind both DNA and RNA in vitro and have been involved in different aspects of gene expression, including pre-mRNA splicing, transcription regulation and nuclear retention of mRNA. We have used double-stranded RNA interference in Drosophila S2...
Topics
- Active Transport, Cell Nucleus
- Animals
- Cell Line
- Cell Nucleus
- Cells, Cultured
- Drosophila Proteins
- Drosophila melanogaster
- Fluorescence Recovery After Photobleaching
- Mutation
- Nuclear Proteins
- Protein Binding
- RNA Splicing
- RNA Transport
- RNA, Messenger
