Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p54<sup><i>nrb</i></sup>/NONO Regulates Cyclic AMP-Dependent Glucocorticoid Production by Modulating Phosphodiesterase mRNA Splicing and Degradation

21 Jan 2015

Abstract excerpt

Glucocorticoid production in the adrenal cortex is activated in response to an increase in cyclic AMP (cAMP) signaling. The nuclear protein p54(nrb)/NONO belongs to the Drosophila behavior/human splicing (DBHS) family and has been implicated in several nuclear processes, including transcription, splicing, and RNA export. We previously identified p54(nrb)/NONO as a component of a protein complex that regulates the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hormonal Regulation and Hypertension
Share to Neurobiology and Insect Physiology Research
Share to Phosphodiesterase function and regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25605330
DOI: 10.1128/mcb.00993-14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 26 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p54<sup><i>nrb</i></sup>/NONO Regulates Cyclic AMP-Dependent Glucocorticoid Production by Modulating Phosphodiesterase mRNA Splicing and DegradationPMID 25605330Read ↗

Saying “Yes” to NONO: A Target for Neuroblastoma Therapy?Semantic proximity Read ↗

The Orphan Nuclear Receptors NURR1 and NGFI-B Modulate Aromatase Gene Expression in Ovarian Granulosa Cells: A Possible Mechanism for Repression of Aromatase Expression upon Luteinizing Hormone SurgeSemantic proximity Read ↗

Nucleoredoxin regulates WNT signaling during pituitary stem cell differentiationSemantic proximity Read ↗

Protocadherin 19 (PCDH19) interacts with paraspeckle protein NONO to co-regulate gene expression with estrogen receptor alpha (ERα).Semantic proximity Read ↗

NAT10 governs uterine function and fertility by stabilizing progesterone receptor mRNA via ac <sup>4</sup> C modificationSemantic proximity Read ↗

Nucleolar detention of NONO shields DNA double-strand breaks from aberrant transcriptsSemantic proximity Read ↗

RNA binding is essential for NONO condensates to modulate pre-mRNA processing of super enhancer-associated genes in neuroblastomaSemantic proximity Read ↗

Alternative mRNA Splicing of Corepressors Generates Variants That Play Opposing Roles in Adipocyte DifferentiationSemantic proximity Read ↗

Stable interaction of NONO with DBHS family members upon etoposide-induced DNA damageSemantic proximity Read ↗

Glucocorticoids Mediate Transcriptome-wide Alternative Polyadenylation: Mechanisms and Functional ImplicationsSemantic proximity Read ↗

CNOT6/6L-mediated mRNA degradation in ovarian granulosa cells is a key mechanism of gonadotropin-triggered follicle developmentSemantic proximity Read ↗

Paraspeckle protein p54nrb links Sox9-mediated transcription with RNA processing during chondrogenesis in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.