Article
Transmission distortion of BDNF variants to bipolar disorder type I patients from a South American population isolate.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2006
Kremeyer Barbara, Herzberg Ibi, Garcia Jenny, Kerr Emily, Duque Constanza, Parra Vicky, Vega Jorge, Lopez Carlos, Palacio Carlos, Bedoya Gabriel, Ospina Jorge, Ruiz-Linares Andres
Abstract excerpt
Recent reports have implicated polymorphisms in the brain derived neurotrophic factor (BDNF) gene region in the etiology of several psychiatric phenotypes, including bipolar disorder. Significant disease association has been reported for the G allele at SNP rs6265, which encodes for Valine at position 66 of BDNF (Val66Met), an apparently functional variant of this key BDNF. Here we examined a sample of 224...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.