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Article

Association Between ABCA1 R219K Variant and Alzheimer's Disease: An Updated Meta-Analysis and Systematic Review.

Current Alzheimer research - 1 Jan 2022

Zhao Jinrong, Wang Jinpei, Zhao Dong, Wang Lin, Luo Xiaoe

Abstract excerpt

BACKGROUND: Over a dozen studies have investigated the effect of the R219K variant in the ATP-binding cassette transporter A1 (ABCA1) gene on the risk of Alzheimer's disease (AD), but the results are conflicting. OBJECTIVE: We performed a systematic review and meta-analysis to comprehensively assess the association between the ABCA1 R219K variant and the risk of AD. METHODS: Studies included in the meta-analysis...

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PMID: 36380407
DOI: 10.2174/1567205020666221114112838

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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