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Article

Quantitative assessment of the effect of ABCA1 gene polymorphism on the risk of Alzheimer's disease.

Molecular biology reports - 1 Feb 2013

Wang Xiao-Feng, Cao Yuan-Wu, Feng Zhen-Zhou, Fu Da, Ma Yu-Shui, Zhang Feng, Jiang Xiao-Xing, Shao Yun-Chao

Abstract excerpt

ATP-binding cassette transporter A1 (ABCA1) is a membrane-associated protein which has attracted considerable attention as a candidate gene for Alzheimer's disease (AD) based on its function as a key factor in lipid metabolism by mediating cellular cholesterol efflux, the rate-limiting step in the production of nascent high-density lipoprotein (HDL) particles. The relationship between ABCA1 common variations...

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Source

Identifiers

PMID: 23111454
DOI: 10.1007/s11033-012-2115-9

Genes

ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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