Article
The functional domains of the murine Thy-1 gene promoter.
Molecular and cellular biology - 1 Apr 1991
Spanopoulou E, Giguere V, Grosveld F
Abstract excerpt
The Thy-1 gene promoter resembles a "housekeeping" promoter in that it is located within a methylation-free island, lacks a canonical TATA box, and displays heterogeneity in the 5'-end termini of the mRNA. Using transgenic mice, we show that this promoter does not confer any tissue specificity an...
Topics
- Animals
- Antigens, Surface
- Base Sequence
- Binding Sites
- Brain
- Deoxyribonuclease I
- Humans
- Mice
- Mice, Transgenic
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Sp1 Transcription Factor
- T-Lymphocytes
- Thy-1 Antigens