Article
The functional domains of the murine Thy-1 gene promoter.
Molecular and cellular biology - 1 Apr 1991
Spanopoulou E, Giguere V, Grosveld F
Abstract excerpt
The Thy-1 gene promoter resembles a "housekeeping" promoter in that it is located within a methylation-free island, lacks a canonical TATA box, and displays heterogeneity in the 5'-end termini of the mRNA. Using transgenic mice, we show that this promoter does not confer any tissue specificity and is active only in a position-dependent manner. It can only be activated in a tissue-specific manner by elements that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
