Functional study of the human thyroid peroxidase gene promoter.

doi:10.1111/j.1432-1033.1992.tb16571.x

Back to search

Article

Functional study of the human thyroid peroxidase gene promoter.

European journal of biochemistry - 1 Feb 1992

Abramowicz M J, Vassart G, Christophe D

Abstract excerpt

Structure/function relationships in the human thyroid peroxidase gene promoter have been studied by deletion and mutation analyses and confronted with footprint patterns obtained with thyroid nuclear extracts and the purified thyroid transcription factor TTF-1. Crude nuclear extracts from dog thy...

Topics

Animals
Base Sequence
Cell Nucleus
Cells, Cultured
Colforsin
DNA
Dogs
Growth Hormone
Humans
Molecular Sequence Data
Mutagenesis, Site-Directed
Mutation
Nuclear Proteins
Peroxidases
Plasmids
Promoter Regions, Genetic
Structure-Activity Relationship
Thyroid Gland

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.