Article
Functional study of the human thyroid peroxidase gene promoter.
European journal of biochemistry - 1 Feb 1992
Abramowicz M J, Vassart G, Christophe D
Abstract excerpt
Structure/function relationships in the human thyroid peroxidase gene promoter have been studied by deletion and mutation analyses and confronted with footprint patterns obtained with thyroid nuclear extracts and the purified thyroid transcription factor TTF-1. Crude nuclear extracts from dog thyroid primary cultures were shown to contain a binding activity recognizing the -119 to -105 segment of the promoter...
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