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Genetic Changes That Correlate with Reduced Susceptibility to Daptomycin in <i>Staphylococcus aureus</i>

24 May 2006

Abstract excerpt

Daptomycin is a lipopeptide antibiotic with potent activity against gram-positive bacteria. Complete-genome comparisons of laboratory-derived Staphylococcus aureus with decreased susceptibility to daptomycin and their susceptible parent were used to identify genes that contribute to reduced susceptibility to daptomycin. Selective pressure of growth in sublethal concentrations of daptomycin resulted in the...

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PMID: 16723576
DOI: 10.1128/aac.00039-06

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Genetic Changes That Correlate with Reduced Susceptibility to Daptomycin in <i>Staphylococcus aureus</i>PMID 16723576Read ↗

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