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Article

A common genetic system for functional studies of pitrilysin and related M16A proteases.

The Biochemical journal - 15 Aug 2006

Alper Benjamin J, Nienow Tatyana E, Schmidt Walter K

Abstract excerpt

Pitrilysin is a bacterial protease that is similar to the mammalian insulin-degrading enzyme, which is hypothesized to protect against the onset of Alzheimer's disease, and the yeast enzymes Axl1p and Ste23p, which are responsible for production of the a-factor mating pheromone in Saccharomyces cerevisiae. The lack of a phenotype associated with pitrilysin deficiency has hindered studies of this enzyme. Herein,...

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Source

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Identifiers

PMID: 16722821
DOI: 10.1042/BJ20060311
PMCID: PMC1525005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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