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Article

Proteasome beta-type subunits: unequal roles of propeptides in core particle maturation and a hierarchy of active site function.

Journal of molecular biology - 27 Aug 1999

Jäger S, Groll M, Huber R, Wolf D H, Heinemeyer W

Abstract excerpt

The 26 S proteasome is a large eukaryotic protease complex acting in ubiquitin-mediated degradation of abnormal and many short-lived, regulatory proteins. Its cylinder-shaped 20 S proteolytic core consists of two sets, each of seven different alpha and beta-type subunits arranged into two outer alpha-rings surrounding two inner beta-rings. The beta-rings form a central chamber with a total of six proteolytically...

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Identifiers

PMID: 10452902
DOI: 10.1006/jmbi.1999.2995

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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