Article
Molecular Characterization of KRAS, BRAF, and EGFR Genes in Cases with Prostatic Adenocarcinoma; Reporting Bioinformatics Description and Recurrent Mutations.
Clinical laboratory - 1 Jan 2015
Salmaninejad Arash, Ghadami Shirin, Dizaji Majid Zaki, Golchehre Zahra, Estiar Mehrdad Asghari, Zamani Mohammad Reza, Ebrahimzadeh-Vesal Reza, Nowroozi Mohammad Reza, Shakoori Abbas
Abstract excerpt
BACKGROUND: Prostate cancer is one of the most common cancers which develops by mutations and/or other genetic alterations in specific genes. Regarding the previous studies in literature predominant mutations take place in KRAS, BRAF, and EGFR genes in special types of cancers. In this research, we attempt to identify the prevalence and significant role of the possible mutations in EGFR exons 18-21, KRAS codon...
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