Article
Identification of recurrent BRAF non-V600 mutations in intraductal carcinoma of the prostate in Chinese populations.
Neoplasia (New York, N.Y.) - 1 Apr 2024
Hu Jing, Chen Xinyi, Sun Feifei, Liu Lili, Liu Long, Yang Zimeng, Zhang Hanwen, Yu Zeyuan, Zhao Ru, Wang Yueyao, Liu Hui, Yang Xiaorong, Sun Fusheng, Han Bo
Abstract excerpt
While BRAF alterations have been established as a driver in various solid malignancies, the characterization of BRAF alterations in prostate cancer (PCa) has not been thoroughly interrogated. By bioinformatics analysis, we first found that BRAF alterations were associated with advanced PCa and exhibited mutually exclusive pattern with ERG alteration across multiple cohorts. Of the most interest, recurrent...
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