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Identification of frequent BRAF copy number gain and alterations of RAF genes in chinese prostate cancer

25 Jul 2012

Abstract excerpt

We recently found that TMPRSS2:ERG fusion genes and PTEN loss, which are common in Western prostate cancers are infrequent in Chinese cases. As previous studies indicated a higher frequency of RAS and BRAF mutation rates in Eastern Asian than in Western prostate cancers and fusion genes involving the RAF family genes BRAF and RAF1 were recently identified in prostate cancer in the American population, we...

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PMID: 22833462
DOI: 10.1002/gcc.21984

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