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Article

Lack of association of IL-10 promoter gene variants with type 1 diabetes in a French population.

Human immunology - 1 Jan 2000

Reynier Frederic, Cazalis Marie-Angelique, Lecoq Annick, Paye Malick, Rosa Audrey, Durand Annie, Jhumka Umar, Mougin Bruno, Miossec Pierre, Bendelac Nathalie, Nicolino Marc, Thivolet Charles

Abstract excerpt

Although genetic predisposition to type 1 diabetes shows a strong association with human leukocyte antigen (HLA) class II alleles, additional genes may influence the immune process and the progression of beta cell loss. Preliminary reports suggested that IL-10 gene polymorphisms contribute to susceptibility to type 1 diabetes. We analyzed the frequencies of three main variants of the promoter region of the IL-10...

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Identifiers

PMID: 16720211
DOI: 10.1016/j.humimm.2006.02.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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