An interleukin-10 gene promoter polymorphism (-592A/C) associated with type 2 diabetes: a North Indian study.

doi:10.1007/s10528-012-9499-z

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An interleukin-10 gene promoter polymorphism (-592A/C) associated with type 2 diabetes: a North Indian study.

Biochemical genetics - 1 Aug 2012

Saxena Madhukar, Agrawal C C, Bid Hemant Kumar, Banerjee Monisha

Abstract excerpt

In this first report on the association of an IL-10 promoter polymorphism with type 2 diabetes mellitus in a North Indian population, the -592A/C SNP (rs1800872) was genotyped by PCR-RFLP and the IL-10 level measured using ELISA. Although no significant difference was observed in the genotypic frequencies (P = 0.657), diabetes patients carried a significantly higher number of A alleles at the -592 position, 25.6%...

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PMID: 22298356
DOI: 10.1007/s10528-012-9499-z

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