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A study on the association of IL-10 promoter polymorphisms with rheumatic heart disease in Turkish female patients.

Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir - 1 Jan 2022

Akadam-Teke Ayşegül Başak, Teker Erhan

Abstract excerpt

OBJECTIVE: Rheumatic heart disease (RHD) is an inflammatory disease that develops after streptococcal infections. The pleiotropic effect of IL-10 plays a role in the regulation of immune system responses. However, impaired IL-10 expression or signaling can impair antigen clearance during acute bacterial infections, creating a favorable environment for persistent inflammation. More than 30 single nucleotide...

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PMID: 35197229
DOI: 10.5543/tkda.2022.77756

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