Article
Variants of the interleukin-10 promoter gene are associated with obesity and insulin resistance but not type 2 diabetes in caucasian italian subjects.
Diabetes - 1 May 2006
Scarpelli Daniela, Cardellini Marina, Andreozzi Francesco, Laratta Emanuela, Hribal Marta Letizia, Marini Maria Adelaide, Tassi Vittorio, Lauro Renato, Perticone Francesco, Sesti Giorgio
Abstract excerpt
Interleukin (IL)-10 is a major anti-inflammatory cytokine that has been associated with obesity and type 2 diabetes. The three polymorphisms -1082G/A, -819C/T, and -592C/A in the IL10 promoter were reported to influence IL10 transcription. We investigated whether these polymorphisms were associat...
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