Article
Interleukin-10 polymorphisms in Spanish type 1 diabetes patients.
Genes and immunity - 1 Jun 2004
Urcelay E, Santiago J L, de la Calle H, Martínez A, Figueredo A, Fernández-Arquero M, de la Concha E G
Abstract excerpt
The MHC accounts for half of the genetic susceptibility to type 1 diabetes (T1D). Evidence suggests that an imbalance in Th1/Th2 responses may play a key role in the development of autoimmune diabetes. Since interleukin-10 (IL-10) modulates immune and inflammatory responses and has been implicated in many autoimmune diseases, it seemed interesting to examine whether IL-10 polymorphisms participate in diabetes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.