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Article

Interleukin-10 gene promoter polymorphisms in celiac patients from north-eastern Italy.

Human immunology - 1 Jul 2014

Zupin Luisa, Polesello Vania, Catamo Eulalia, Crovella Sergio, Segat Ludovica

Abstract excerpt

Celiac disease is a complex chronic intestinal disorder driven by an immune response against the gliadin fraction of gluten: many factors are involved in the pathogenesis of the disease, and among these Interleukin-10 could play an important role. In the present study, the -1082A>G, -819T>C and -592A>C IL10 functional polymorphisms were analyzed in 565 celiac patients and 576 healthy controls from north-eastern...

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PMID: 24768947
DOI: 10.1016/j.humimm.2014.04.011

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