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Article

Gab1 signaling is regulated by EGF receptor sorting in early endosomes.

Oncogene - 26 Oct 2006

Kostenko O, Tsacoumangos A, Crooks D, Kil S J, Carlin C

Abstract excerpt

Although combinatorial signaling through the ErbB network is implicated in certain types of human cancer, the specifics of how particular receptors contribute to the transformed phenotype are not well understood. The goal of this study was to identify epidermal growth factor (EGF) receptor-dependent cell signaling abnormalities specifically associated with mutations in a previously described 679-LL lysosomal...

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Source

Identifiers

PMID: 16715136
DOI: 10.1038/sj.onc.1209675

Genes

EGF
EEA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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