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Article

EGFR mutations and abnormal trafficking in cancers.

Molecular biology reports - 21 Aug 2024

Kang Xiang, Li Rendong, Li Xiaolei, Xu Xinping

Abstract excerpt

Epidermal growth factor receptor (EGFR) is a transmembrane tyrosine kinase receptor and a member of the ErbB receptor family. As a significant cancer driver, EGFR undergoes mutations such as gene amplification or overexpression in a wide range of malignant tumors and is closely associated with tumorigenesis. This review examines the aberrant expression of EGFR in several common cancers and summarizes the current...

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Identifiers

PMID: 39167290
DOI: 10.1007/s11033-024-09865-z

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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