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Article

Two PEST-like motifs regulate Ca2+/calpain-mediated cleavage of the CaVbeta3 subunit and provide important determinants for neuronal Ca2+ channel activity.

The European journal of neuroscience - 1 May 2006

Sandoval Alejandro, Oviedo Norma, Tadmouri Abir, Avila Traudy, De Waard Michel, Felix Ricardo

Abstract excerpt

An increase in intracellular Ca2+ due to voltage-gated Ca2+ (CaV) channel opening represents an important trigger for a number of second-messenger-mediated effects ranging from neurotransmitter release to gene activation. Ca2+ entry occurs through the principal pore-forming protein but several ancillary subunits are known to more precisely tune ion influx. Among them, the CaVbeta subunits are perhaps the most...

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Identifiers

PMID: 16706839
DOI: 10.1111/j.1460-9568.2006.04749.x
PMCID: PMC2700823

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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