Article
A combination of single nucleotide polymorphisms is associated with the interindividual variability in the blood lipid response to dietary fatty acid consumption in a randomized clinical trial.
The American journal of clinical nutrition - 2 Aug 2021
Rajendiran Ethendhar, Lamarche Benoît, She Yongbo, Ramprasath Vanu, Eck Peter, Brassard Didier, Gigleux Iris, Levy Emile, Tremblay Angelo, Couture Patrick, House James D, Jones Peter J H, Desmarchelier Charles
Abstract excerpt
BACKGROUND: Blood lipid concentrations display high interindividual variability in response to dietary interventions, partly due to genetic factors. Existing studies have focused on single nucleotide polymorphisms (SNPs) analyzed individually, which only explain a limited fraction of the variability of these complex phenotypes. OBJECTIVE: We aimed to identify combinations of SNPs associated with the variability...
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