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Article

Evidence for consistent intragenic and intergenic interactions between SNP effects in the APOA1/C3/A4/A5 gene cluster.

Human heredity - 1 Jan 2006

Hamon Sara C, Kardia Sharon L R, Boerwinkle Eric, Liu Kiang, Klos Kathy L E, Clark Andrew G, Sing Charles F

Abstract excerpt

OBJECTIVE: Evaluate the consistency of the contribution of interactions between single nucleotide polymorphism (SNP) genotype effects to variation in measures of lipid metabolism across ethnic strata within gender. METHODS AND RESULTS: We considered 80 SNPs within the apolipoprotein (APO) A1/C3/A4/A5 gene cluster using an over-parameterized general linear model to identify SNPs whose genotype effects combine...

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Source

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Identifiers

PMID: 16710093
DOI: 10.1159/000093384
PMCID: PMC1698960

Genes

APOA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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