Article
Integrated role of two apoliprotein E polymorphisms on apolipoprotein B levels and coronary artery disease in a biethnic population.
Metabolic syndrome and related disorders - 1 Dec 2010
Ozturk Zeynep, Enkhmaa Byambaa, Shachter Neil S, Berglund Lars, Anuurad Erdembileg
Abstract excerpt
BACKGROUND: Apolipoprotein E (ApoE) plays a major role in lipoprotein metabolism and genetic variability of ApoE confers susceptibility to coronary artery disease (CAD). Beyond variability in the coding region, promoter polymorphisms in the ApoE gene impact on ApoE transcription. METHODS: We determined the ApoE - 491 A/T promoter polymorphism, ApoE isoforms, lipid and lipoprotein levels, and CAD risk factors in...
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