Article
Association study of the PIN1 gene with Alzheimer's disease.
Neuroscience letters - 24 Jul 2006
Lambert Jean-Charles, Bensemain Faiza, Chapuis Julien, Cottel Dominique, Amouyel Philippe
Abstract excerpt
Genetic linkage studies indicate evidence for one or more Alzheimer's disease (AD) genes on chromosome 19 independently of the apolipoprotein E gene, a well-characterized AD-risk factor. Recently, the PIN1 gene on chromosome 19p13.2 has been proposed as a candidate gene for AD. Here, we have investigated the potential impact of two promoter polymorphisms (rs2233678 and rs2233679) within this gene on the risk of...
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