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Article

kappa-casein-deficient mice fail to lactate.

Proceedings of the National Academy of Sciences of the United States of America - 23 May 2006

Shekar P Chandra, Goel Sandeep, Rani S Deepa Selvi, Sarathi D Partha, Alex Jomini Liza, Singh Shashi, Kumar Satish

Abstract excerpt

Acquisition of milk production capabilities by an ancestor of mammals is at the root of mammalian evolution. Milk casein micelles are a primary source of amino acids and calcium phosphate to neonates. To understand the role of kappa-casein in lactation, we have created and characterized a null mouse strain (Csnk-/-) lacking this gene. The mutant kappa-casein allele did not affect the expression of other milk...

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Identifiers

PMID: 16698927
DOI: 10.1073/pnas.0601611103
PMCID: PMC1472419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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