Article
Mex3c mutation affects lactation through impairing milk ejection in female mice.
Bioscience reports - 23 Dec 2020
Du Yong, Sun Dongjun, Li Yan
Abstract excerpt
Mouse Mex3c encodes RNA-binding proteins of variant length through alternative splicing. Its mutation results in multiple defects including growth retardation, perturbed energy balance, and defective antiviral innate immunity. Here we report that Mex3c mutation affects mammary gland development and lactation in female mice. Pups of Mex3c mutant dams die of starvation soon after birth. Milk contents are present in...
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