Creation and phenotypic analysis of alpha-lactalbumin-deficient mice.

doi:10.1073/pnas.91.14.6544

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Article

Creation and phenotypic analysis of alpha-lactalbumin-deficient mice.

Proceedings of the National Academy of Sciences of the United States of America - 5 Jul 1994

Stinnakre M G, Vilotte J L, Soulier S, Mercier J C

Abstract excerpt

alpha-Lactalbumin is an abundant milk-specific calcium metalloprotein which has an evolutionary relationship to lysozyme. It modifies the substrate specificity of a Golgi galactosyltransferase by forming the lactose synthetase binary complex. Lactose, together with other sugars and diffusible ions, is responsible for the osmotic pressure of milk. To assess the involvement of alpha-lactalbumin in lactogenesis,...

Topics

Animals
Blotting, Northern
Blotting, Southern
Chimera
Crosses, Genetic
Embryo, Mammalian
Female
Fertility
Genetic Vectors
Heterozygote
Homozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lactalbumin

Lactation

Male

Mammary Glands, Animal

Mice

Mice, Inbred BALB C

Mice, Inbred CBA

Source

Open in PubMed Open full text

Identifiers

PMID: 8022817
DOI: 10.1073/pnas.91.14.6544
PMCID: PMC44239

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8022817-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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