Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative analysis of enzyme activities and mRNA levels of peptidyl prolyl cis/trans isomerases in various organs of wild type and Pin1-/- mice.

FEBS letters - 29 May 2006

Fanghänel Jörg, Akiyama Hirotada, Uchida Chiyoko, Uchida Takafumi

Abstract excerpt

We investigated the enzyme activity of peptidyl prolyl cis/trans isomerases (PPIases) in brain, testis, lung, liver, and mouse embryonic fibroblasts (MEF) of Pin1+/+ and Pin1-/- mice. The aim of this study is to determine if other PPIases can substitute for the loss of Pin1 activity in Pin1-/- mice and what influence Pin1 depletion has on the activities of other PPIases members. The results show that high PPIase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclophilins
Share to Fibroblasts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to NIMA-Interacting Peptidylprolyl Isomerase

Share to Peptidylprolyl Isomerase

Share to Tacrolimus Binding Proteins

Share to Testis

Share to Tissue Distribution

Source

Identifiers

PMID: 16697379
DOI: 10.1016/j.febslet.2006.04.087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative analysis of enzyme activities and mRNA levels of peptidyl prolyl cis/trans isomerases in various organs of wild type and Pin1-/- mice.PMID 16697379Read ↗

Biological Function of Pin1 in Vivo and Its Inhibitors for Preclinical Study: Early Development, Current Strategies, and Future DirectionsSemantic proximity Read ↗

Prolyl Isomerase Pin1 in Human Cancer: Function, Mechanism, and SignificanceSemantic proximity Read ↗

The role of the master cancer regulator Pin1 in the development and treatment of cancerSemantic proximity Read ↗

Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes.Semantic proximity Read ↗

The kingdom of the prolyl-isomerase Pin1: The structural and functional convergence and divergence of Pin1Semantic proximity Read ↗

Pinning Down Signaling in the Immune System: The Role of the Peptidyl-Prolyl Isomerase Pin1 in Immune Cell FunctionSemantic proximity Read ↗

Oncogenic Hijacking of the PIN1 Signaling NetworkSemantic proximity Read ↗

Targeting carcinogenesis: A role for the prolyl isomerase Pin1?Semantic proximity Read ↗

A role for Pin1 in mammalian germ cell development and spermatogenesis.Semantic proximity Read ↗

Functional conservation of phosphorylation-specific prolyl isomerases in plants.Semantic proximity Read ↗

Prevalent overexpression of prolyl isomerase Pin1 in human cancers.Semantic proximity Read ↗

Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G(0) arrest.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.