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Article

Oncogenic Hijacking of the PIN1 Signaling Network

25 Feb 2019

Abstract excerpt

Cellular choices are determined by developmental and environmental stimuli through integrated signal transduction pathways. These critically depend on attainment of proper activation levels that in turn rely on post-translational modifications (PTMs) of single pathway members. Among these PTMs, post-phosphorylation prolyl-isomerization mediated by PIN1 represents a unique mechanism of spatial, temporal and...

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Identifiers

PMID: 30873382
DOI: 10.3389/fonc.2019.00094

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