Article
Myocardial substrate metabolism in the normal and failing heart.
Physiological reviews - 1 Jul 2005
Stanley William C, Recchia Fabio A, Lopaschuk Gary D
Abstract excerpt
The alterations in myocardial energy substrate metabolism that occur in heart failure, and the causes and consequences of these abnormalities, are poorly understood. There is evidence to suggest that impaired substrate metabolism contributes to contractile dysfunction and to the progressive left ventricular remodeling that are characteristic of the heart failure state. The general concept that has recently...
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