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Article

Activation and roles of ALK4/ALK7-mediated maternal TGFbeta signals in zebrafish embryo.

Biochemical and biophysical research communications - 30 Jun 2006

Sun Zhihui, Jin Peng, Tian Tian, Gu Yi, Chen Ye-Guang, Meng Anming

Abstract excerpt

Activin, Nodal, and Vg1, members of the transforming growth factor beta (TGFbeta) superfamily, transduce signal through type I receptors ALK4 or ALK7 and play important roles in mesoderm induction and patterning during vertebrate embryogenesis. However, the timing and magnitude of the ALK4/ALK7-mediated maternal TGFbeta signals are not clear. SB-431542 is identified as an inhibitor of the ALK4/ALK5/ALK7-mediated...

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PMID: 16696945
DOI: 10.1016/j.bbrc.2006.04.148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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