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Article

The novel type I serine-threonine kinase receptor Alk8 binds TGF-beta in the presence of TGF-betaRII.

Biochemical and biophysical research communications - 24 May 2002

de Caestecker Mark P, Bottomley Martyn, Bhattacharyya Sucharita, Payne Tracie L, Roberts Anita B, Yelick Pamela C

Abstract excerpt

The TGF-beta superfamily consists of an array of ligands including BMP, TGF-beta, activin, and nodal subfamilies. The extensive range of biological effects elicited by TGF-beta family signaling is due in part to the large numbers and promiscuity of types I and II TGF-beta family member receptors. Alk8 is a novel type I TGF-beta family member receptor first identified in zebrafish [Dev. Dyn. 211 (4) (1998) 352],...

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PMID: 12054694
DOI: 10.1016/S0006-291X(02)00424-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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