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Article

Lactosylceramide is required in apoptosis induced by N-Smase.

Glycoconjugate journal - 1 May 2006

Martin Sergio F, Williams Niesha, Chatterjee Subroto

Abstract excerpt

Lactosylceramide (LacCer) is a member of the glycosphingolipid family which has been recently recognized as a signaling intermediate in the regulation of cell proliferation and cell adhesion. In this paper, we present our studies pointing to a potential role of LacCer in inducing apoptosis. In our studies we employed a human osteosarcoma cell line MG-63 (wild type, WT) and a neutral sphingomyelinase (N-SMase)...

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Identifiers

PMID: 16691498
DOI: 10.1007/s10719-006-7920-8

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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