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Article

Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis.

The Journal of biological chemistry - 9 Jan 2004

Reiss Ulrike, Oskouian Babak, Zhou Jianhui, Gupta Vinita, Sooriyakumaran Prathap, Kelly Samuel, Wang Elaine, Merrill Alfred H, Saba Julie D

Abstract excerpt

Sphingosine-1-phosphate lyase is a widely expressed enzyme that catalyzes the essentially irreversible cleavage of the signaling molecule sphingosine 1-phosphate. To investigate whether sphingosine-1-phosphate lyase influences mammalian cell fate decisions, a recombinant human sphingosine-1-phosp...

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PMID: 14570870
DOI: 10.1074/jbc.M309646200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14570870-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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