Article
The two eIF4A helicases in Trypanosoma brucei are functionally distinct.
Nucleic acids research - 1 Jan 2006
Dhalia Rafael, Marinsek Nina, Reis Christian R S, Katz Rodolfo, Muniz João R C, Standart Nancy, Carrington Mark, de Melo Neto Osvaldo P
Abstract excerpt
Protozoan parasites belonging to the family Trypanosomatidae are characterized by an unusual pathway for the production of mRNAs via polycistronic transcription and trans-splicing of a 5' capped mini-exon which is linked to the 3' cleavage and polyadenylation of the upstream transcript. However, little is known of the mechanism of protein synthesis in these organisms, despite their importance as agents of a...
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