Article
Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins.
Development (Cambridge, England) - 1 Jun 2006
Matakatsu Hitoshi, Blair Seth S
Abstract excerpt
The protocadherins Fat (Ft) and Dachsous (Ds) are required for several processes in the development of Drosophila, including controlling growth of imaginal discs, planar cell polarity (PCP) and the proximodistal patterning of appendages. Ft and Ds bind in a preferentially heterophilic fashion, and Ds is expressed in distinct patterns along the axes of polarity. It has thus been suggested that Ft and Ds serve not...
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