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Article

Planar polarity from flies to vertebrates.

Journal of cell science - 1 Feb 2004

Fanto Manolis, McNeill Helen

Abstract excerpt

Planar cell polarity (PCP) has been demonstrated in the epithelium of organisms from flies to humans. Recent research has revealed that the planar organization of cells requires a conserved set of genes, known as the PCP genes. Tbe PCP proteins Frizzled (Fz) and Dishevelled (Dsh) function as key players in PCP signalling. Although Fz and Dsh are also involved in Wingless (Wg)/Wnt signalling, these proteins have...

Topics

Adaptor Proteins, Signal Transducing
Animals
Cell Polarity
Dishevelled Proteins
Drosophila
Drosophila Proteins
Frizzled Receptors
Humans
Membrane Proteins
Mutation
Phosphoproteins
Proto-Oncogene Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, G-Protein-Coupled

Signal Transduction

Vertebrates

Wnt1 Protein

Source

Identifiers

PMID: 14730010
DOI: 10.1242/jcs.00973

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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