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Article

The thrombospondin-1 N700S polymorphism is associated with early myocardial infarction without altering von Willebrand factor multimer size.

Blood - 15 Aug 2006

Zwicker Jeffrey I, Peyvandi Flora, Palla Roberta, Lombardi Rossana, Canciani Maria Teresa, Cairo Andrea, Ardissino Diego, Bernardinelli Luisa, Bauer Kenneth A, Lawler Jack, Mannucci Pier

Abstract excerpt

The N700S polymorphism of thrombospondin-1 (TSP-1) has been identified as a potential genetic risk factor for myocardial infarction (MI). In a large case-control study of 1425 individuals who survived a myocardial infarction prior to age 45, the N700S polymorphism was a significant risk factor for myocardial infarction in both homozygous (odds ratio [OR] 1.9, 95% confidence interval [CI] 1.1-3.3, P = .01) and...

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Identifiers

PMID: 16684956
DOI: 10.1182/blood-2006-04-015701
PMCID: PMC1895875

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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