Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A mutation in the thrombomodulin gene, 127G to A coding for Ala25Thr, and the risk of myocardial infarction in men.

Thrombosis and haemostasis - 1 Nov 1998

Doggen C J, Kunz G, Rosendaal F R, Lane D A, Vos H L, Stubbs P J, Manger Cats V, Ireland H

Abstract excerpt

Thrombomodulin is an endothelial cell surface receptor that transforms the procoagulant thrombin into an anticoagulant. A mutation in the thrombomodulin gene is a potential risk factor for venous and arterial thrombosis. We screened a region within the coding sequence of the thrombomodulin gene by single-strand conformation polymorphism analysis (SSCP) in a pilot study of 104 patients with myocardial infarction...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Amino Acid Substitution

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Genetic Predisposition to Disease

Share to Point Mutation

Share to Polymorphism, Single-Stranded Conformational

Share to Risk Factors

Source

Identifiers

PMID: 9843165

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A mutation in the thrombomodulin gene, 127G to A coding for Ala25Thr, and the risk of myocardial infarction in men.PMID 9843165Read ↗

Thrombomodulin gene mutations associated with myocardial infarction.Semantic proximity Read ↗

The thrombomodulin gene mutation G(127)-->A (Ala25Thr) and cerebrovascular disease.Semantic proximity Read ↗

Role of thrombomodulin gene in Indian population with coronary artery disease.Semantic proximity Read ↗

Functional mutation in the promoter region of thrombomodulin gene in relation to carotid atherosclerosis.Semantic proximity Read ↗

Synergistic effect of thrombomodulin promoter -33G/A polymorphism and smoking on the onset of acute myocardial infarction.Semantic proximity Read ↗

Thrombomodulin Ala455Val polymorphism and risk of coronary heart disease.Semantic proximity Read ↗

Genetic variation in the human thrombomodulin promoter locus and prognosis after acute coronary syndrome.Semantic proximity Read ↗

Thrombomodulin -33G/A and Ala455Val polymorphisms are associated with the risk of coronary artery disease: a meta-analysis including 12 584 patients.Semantic proximity Read ↗

Association study of polymorphism in Thrombomodulin gene [rs1042579] with cardiovascular disease.Semantic proximity Read ↗

Association of Thrombomodulin Gene Polymorphisms with Susceptibility to Atherosclerotic Diseases: A Meta-Analysis.Semantic proximity Read ↗

A common thrombomodulin amino acid dimorphism is associated with myocardial infarction.Semantic proximity Read ↗

Mutations in the thrombomodulin gene are rare in patients with severe thrombophilia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.