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Article

Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2002

Boekholdt S Matthijs, Trip Mieke D, Peters Ron J G, Engelen Marc, Boer Jolanda M A, Feskens Edith J M, Zwinderman Aeilko H, Kastelein John J P, Reitsma Pieter H

Abstract excerpt

OBJECTIVE: Recently, polymorphisms in thrombospondin (THBS) genes coding for THBS-1 (N700S), THBS-2 (T>G substitution in 3'-untranslated region), and THBS-4 (A387P) genes were proposed to modulate the risk of premature coronary artery disease (CAD) or myocardial infarction (MI). It was our objective to verify this hypothesis in an independent cohort. METHODS AND RESULTS: We performed a case-control study among...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12482844
DOI: 10.1161/01.atv.0000046235.22451.66

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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