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Article

An association study of thrombospondin 1 and 2 SNPs with coronary artery disease and myocardial infarction among South Indians.

Thrombosis research - 1 Oct 2011

Ashokkumar Manickaraj, Anbarasan Chakrapani, Saibabu Ramineni, Kuram Sriram, Raman Suresh C, Cherian Koothurathu Mammen

Abstract excerpt

INTRODUCTION: Thrombospondin 1 and 2 are multidomain calcium-binding extracellular glycoproteins and they play a role in platelet aggregation, inflammatory response and assembly of connective tissue extracellular matrix. The association of thrombospondins (TSP) in the pathogenesis of coronary artery disease (CAD) and myocardial infarction (MI) is well established. The association of the TSP-1 (Asn700Ser, 2210A →...

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PMID: 21762961
DOI: 10.1016/j.thromres.2011.05.026

Genes

CAD

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