Article
Regulation of ras p21 by GTPase activating proteins.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 1991
McCormick F, Martin G A, Clark R, Bollag G, Polakis P
Abstract excerpt
We propose a model for dual effector functions of the known ras GAPs p120-GAP and NF1-GAP. This model is consistent with known biological and biochemical effects of GAPs in mammalian cells, but it is clearly not a proven hypothesis, and several difficulties remain in making this model convincing. One is the apparent difference between mammalian cells and yeasts, in which GAPs do not have a demonstrable effector...
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