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Article

Differences in GTPase-activating protein activity between liver tumors and normal liver tissue in mice.

Oncogene - 1 Jul 1992

Müller O, Frech M, Gideon P, Wittinghofer A, Schwarz M

Abstract excerpt

The intrinsic GTPase activity of the cellular protein p21ras is strongly increased by two cytosolic proteins, the GTPase-activating protein (GAP) produced by the neurofibromatosis type 1 gene (NF1-GAP) and a GAP of 120 kDa molecular mass (p120-GAP). The GAP-mediated stimulation of p21ras GTPase activity was measured in cytosol obtained from carcinogen-induced liver tumors and normal liver tissues of mice of two...

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PMID: 1620552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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