Article
Effects of the ras-related rap2 protein on cellular proliferation.
International journal of cancer - 30 Sept 1991
Jimenez B, Pizon V, Lerosey I, Béranger F, Tavitian A, de Gunzburg J
Abstract excerpt
Ras oncogenes encode 21-kDa (p21s) GTP binding proteins that are capable of transforming immortalized cells in culture. The ras-related rap1A/Krev-1/smgp21A protein, that exhibits a similar structural organization and contains the same effector domain as ras proteins, antagonizes ras-transformation. In order to investigate whether the closely related (61% identical) rap2 protein had similar capacities, the...
Topics
- Animals
- Base Sequence
- Cell Division
- Cell Line, Transformed
- Gene Products, vpr
- Genes, ras
- Molecular Sequence Data
- Mutation
- Phenotype
- Rats
- Transfection